Additional information can be found at www.bravecto.com. Pyriproxifen (flea sterilizer) Dog. Bravecto for dogs is a chewable tablet that delivers 12 weeks of flea and tick protection. Dosage. Peak fluralaner concentrations are achieved between 2 hours and 3 days following oral administration, and the elimination half-life ranges between 9.3 to 16.2 days. Bravecto doesn’t have a chewable for cats, only dogs. Abnormal salivation was observed on 17 occasions: in six treated dogs (11 occasions) after dosing and four control dogs (6 occasions). Caution in cats with concurrent neurologic disease, adverse reactions can rarely include: lethargy, tremors, appetite loss, seizures. A single dose of BRAVECTO Chew should be given to the dog by mouth with food. Updated: 2020-12-31. Bravecto began to kill fleas within two hours after administration in a well-controlled laboratory study. We cannot confirm the completeness, accuracy and currency of the content. Repels and kills ticks, fleas and mosquitoes; For dogs 7 weeks of age or older; Convenient and easy to apply monthly topical treatment; Waterproof and fragrance free Copyright © 2021 Animalytix LLC. If you would like to know why we haven’t included over the counter products (as would be sold in a grocery or pet supply store), click here. A study shows that 91 percent of canines happily take the medication. Bravecto for Dogs has been proven safe for puppies over 8 weeks old, weighing at least 2 kg along with breeding, pregnant and lactating dogs. Dermal Dose: >5,000 mg/kg in rats Orally: 450 mg/kg in rats, Imidacloprid Dermal Dose: >5,000 mg/kg in rats Imidacloprid Orally: 450 mg/kg in rats >4,000 mg/kg in rats for Permethrin, Imidacloprid Dermal Dose: >5,000 mg/kg in rats Imidacloprid Orally: 450 mg/kg in rats >2,000 mg/kg in rabbits for Moxidectin, Fipronil Dermal Dose: >5,000 mg/kg in rats Fipronil Orally: 750 mg/kg in rats; >4,000 mg/kg in rats for topical Permethrin, Fipronil Dermal Dose: >5,000 mg/kg in rats Fipronil Orally: 750 mg/kg in rats Methoprene Orally: >34,600 in rats (virtually non-toxic), Fipronil Dermal Dose: >5,000 mg/kg in rats Fipronil Orally: 750 mg/kg in rats, Indoxacarb must be activated by insect metabolism (no activity in mammals), Indoxacarb is inert in the mammal body, >4,000 mg/kg in rats for Permethrin, Dermal LD50: >2000 mg/kg (rat), Oral LD50: >2000 mg/kg (rat), approx 783 mg/kg in the rat (over 300 times the therapeutic dose in the dog), imidacloprid dermal dose: >5,000 mg/kg in ratsImidacloprid orally: 450 mg/kg in rats, flumethrin: ld50 oral rat (male) 258 mg/kg, ld50 dermal rat > 150 mg/kg, Lufenuron Orally: > 2,000 mg/kg in rats Milbemycin LD50 information unavailable Symptoms of tremors and incoordination result at 19 times recommended dose, www.comfortis4dogs.com (AcuGuard is a private label*), May promote seizures in dogs already predisposed to seizures, Puppies less than 14 weeks of age may experience a higher rate of vomiting. Diarrhea, mucoid and bloody feces were the most common observations in this study, occurring at a similar incidence in the treated and control groups. Other Parasites Killed, Controlled or Repelled, Manufacturer recommends against use but not specifically labeled against, Hookworms, Roundworms, Whipworms & Heartworm, Manufacturer recommends consulting with veterinarian first, Begins Killing Fleas in 4 hours,99% Fleas Dead within 8 hours, Demodectic Mange Mites, Ticks, Sarcoptic Mange Mites, Dogs: Ticks, Ear Mites, Sarcoptic Mange Mites & Heartworm LarvaeCats: Hookworms, Roundworms, Ear Mites & Heartworm Larvae, Greater than 98% of Pre-Existing Fleas Dead within 24 Hours; Then New Fleas Greater than 93.8% within 12 hours, Ticks, Hookworms, Roundworms, Ear Mites, Heartworm, 98% of Pre-Existing Fleas Dead in 12 Hours; Then New Fleas in 2 Hours, Dogs: Whipworms, Hookworms, Roundworms & Heartworm Cats: Hookworms, Roundworms, Ear Mites & Heartworm, daily or as needed (but not more than once a day), 90% of fleas dead in 6 hours, 99% in 12 hours, Frontline, Fiproguard, PetArmor EasySpot (cats) Parastar (dogs) Effipro (cats), 24 Hrs to Translocate, then 4-18 Hours to Kill Fleas, 24 Hrs to Translocate, then 4-18 Hrs to Kill Fleas and 24-48 Hours to Kill Ticks, 99.9% of fleas dead in 72 hours (66% of fleas dead in 24 hours), Ticks, Sarcoptic Mange Mites, Demodectic Mange mites, 12 Weeks(only kills Lone Star ticks for 8 weeks), every 12 weeks for fleas(every 8 weeks for ticks), >96.2% of fleas dead within 8 hours, begins to kills fleas after 3 hours, 24 hours (after that new fleas killed within 2 hours), Ticks, Lice, aids in Sarcoptic Mange control, 8 months (5 months if pet swimsor bathes once a month or more),30 days for lice, Monthly for oral; Every 6 Months for Injectable, Individual ingredients Yes, but combination not approved, Prescription Drug, Non-Prescription Drug or Insectcide, Lethal Dose to 50% of the Population(the higher the number, the safer the product)[What is LD50? One adult treated dog suffered a seizure during the course of the study (46 days after the second treatment). It kills and repels ticks, all life stages of fleas, and mosquitoes on contact before they bite and cause problems for your dog. TRUSTED PROTECTION. * VCA Animal Hospitals and Banfield Pet Hospitals market some products under their own hospital private label, made by the   same manufacterer as the original product. You can administer Bravecto any time, day or night, but it’s best to give him the pork-flavored tablet around feeding time. Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. Fluralaner is an inhibitor of the arthropod nervous system. Advantage II, Combiva, Crossblock II, Paradefense for cats, Provecta for cats. Bravecto Chew for Dogs is approved for use in breeding, pregnant, and lactating dogs. For use in dogs from 11 weeks of age and over 2kg For optimal control of tick and flea infestation, the Bravecto spot-on should be administered at 3 monthly intervals. The edema improved progressively through the day and had resolved without medical intervention by the next morning. Bravecto’s is just called a “tasty chew” and should mimic the generic taste of most dog treats. It may look like the pet has more fleas. One Bravecto for Cats reviewer on Allivet states that it is “the best flea and tick control around. We comply with the HONcode standard for trustworthy health information -, Direction and dosage information for Bravecto. Hello. Margin of Safety Study: In a margin of safety study, Bravecto was administered orally to 8- to 9-week-old puppies at 1, 3, and 5X the maximum label dose of 56 mg/kg at three, 8-week intervals. Simparica might have the edge over Bravecto because liver flavor has been shown to be very useful with dogs. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Bravecto is not effective against lone star ticks beyond 8 weeks of dosing. Provecta Advanced for Dogs is a one-a-month topical prevention and treatment for dogs seven weeks and older that contains the same active ingredients as K9 Advantix II* at a fraction of the cost. Wash hands after using product, as it is irritating to your eyes. Quantifiable drug concentrations can be measured (lower than necessary for effectiveness) through 112 days. Fluralaner is for systemic use and belongs to the class of isoxazoline-substituted benzamide derivatives. Simparica vs. Bravecto Similarities. and cats who weigh at least 2.6 lbs. Adverse reactions can include: lethargy, tremors, appetite loss. The Benefits of Provecta Advanced for Dogs. Adverse reactions can include: lethargy, tremors, appetite loss, seizures. One dog in the 1X treatment group vomited food 4 hours following the first treatment. Every effort has been made to ensure the accuracy of the Bravecto information published above. How Long Until Maximum Effect Against Fleas Is Reached? 2. All potential adverse reactions were recorded in dogs treated with Bravecto over a 182-day period and in dogs treated with the active control over an 84-day period. In a European laboratory study, Bravecto killed fleas and Ixodes ricinus ticks and reduced the numbers of live fleas and Ixodes ricinus ticks on dogs by > 98% within 12 hours for 12 weeks. The following abnormalities were noted in 7 pups from 2 of the 10 dams in only the treated group during gross necropsy examination: limb deformity (4 pups), enlarged heart (2 pups), enlarged spleen (3 pups), and cleft palate (2 pups). Avoid oral ingestion. Imidacloprid. Provecta Advanced is a 5-way parasite treatment for dogs. Bravecto has not been shown to be effective for 12-weeks duration in puppies less than 6 months of age. Bravecto has a wide margin of safety in dogs who weigh at least 4.4 lbs. Copyright © 2014 Intervet Inc, a subsidiary of Merck & Company Inc. That said, it can be notoriously difficult to protect cats with treatments because many cats are indoor/outdoor cats. - Los Angeles, CA 90066 - Phone:(310) 391-6741 - Fax:(310) 391-6744 - Email: MarVistaAMC@gmail.com. Provecta® Advanced for Dogs (Imidacloprid, Pyriproxyfen, Permethrin) is a monthly topical treatment and prevention of ticks, fleas, mosquitoes, biting flies and lice. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. This topical treatment keeps your pup free of itching bug bites for up to one month with a single application! Should not be used in dogs with known seizure disorders, wash hands after using product. In a European laboratory study, Bravecto killed fleas and Ixodes ricinus ticks and reduced the numbers of live fleas and Ixodes ricinus ticks on dogs by > 98% within 12 hours for 12 weeks. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Provecta Advanced For Dogs Provecta Advanced For Dogs is a once-a-month topical flea prevention and treatment for dogs 7 weeks and older. (active ingredients: fipronil, cyphenothrin or etophenprox, methoprene). Adverse reactions can include: lethargy, tremors, appetite loss. Product may be packaged in 1, 2, or 4 chews per package. PROVECTA FOR CATS. Bravecto ® for Dogs is available in two variants: Bravecto ® Chew and Bravecto ® Spot-On for Dogs. This chew will provide your pooch … There were no clinically-relevant, treatment-related effects on the body weights, food consumption, reproductive performance, semen analysis, litter data, gross necropsy (adult dogs) or histopathology findings (adult dogs and puppies). In a well-controlled laboratory dose confirmation study, one dog developed edema and hyperemia of the upper lips within one hour of receiving Bravecto. Bravecto is also indicated for the treatment and control of Amblyomma americanum (lone star tick) infestations for 8 weeks in dogs and puppies 6 months of age and older, and weighing 4.4 pounds or greater. For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS or online at http://www.fda.gov/AnimalVeterinary/SafetyHealth. Provecta Advanced For Dogs is a once-a-month topical flea prevention and treatment for dogs 7 weeks and older. Dogs love the pork flavor and eat tablets like treats. In a well-controlled laboratory study, Bravecto demonstrated 100% effectiveness against adult fleas 48 hours post-infestation for 12 weeks. Speed of action – Bravecto begins killing fleas within 2 hours, and kills most ticks within 12 hours. Wash hands thoroughly with soap and water immediately after use of the product. It is also approved for puppies and kittens aged 6 months or older. Find helpful customer reviews and review ratings for Provecta Advanced For Dogs 21-55 lbs. Bravecto kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), and the treatment and control of tick infestations [Ixodes scapularis (black-legged tick), Dermacentor variabilis (American dog tick), and Rhipicephalus sanguineus (brown dog tick)] for 12 weeks in dogs and puppies 6 months of age and older, and weighing 4.4 pounds or greater. For technical assistance or to report a suspected adverse drug reaction, contact Merck Animal Health at 1-800-224-5318. Product doses are typically <100mg per dose. Bravecto may be administered every 8 weeks in case of potential exposure to Amblyomma americanum ticks (see Effectiveness). deer tick), American dog tick, brown dog tick, and lone star tick. 3850 Grand View Blvd. Bravecto is available in five strengths (112.5, 250, 500, 1000, and 1400 mg fluralaner per chew). Provecta contains the same active ingredients as K9 Advantix II. * Provecta Advanced provides one full month of protection for your dog in a convenient monthly application. Do not eat, drink or smoke while handling the product. It’s still very pleasing to most dogs, but if your dog is particularly picky, you do have different flavor options here. (4 Dose) at Amazon.com. The dogs in the control group (0X) were untreated. Bravecto: in a field study of 294 dogs, reactions included vomiting, decreased appetite, diarrhea, lethargy, and increased drinking. Provecta Advanced for Dogs is a once-a-month topical prevention and treatment for dogs seven weeks and older that contains the same active ingredients as K9 Advantix II. Administering the treatment couldn’t be any easier. Dogs with signs of flea allergy dermatitis showed improvement in erythema, alopecia, papules, scales, crusts, and excoriation as a direct result of eliminating flea infestations. Pyriproxifen (flea sterilizer) Dog or Cat. The most frequently reported adverse reaction in dogs in the Bravecto and active control groups was vomiting. Distributed by: Intervet Inc (d/b/a Merck Animal Health), Summit, NJ 07901. History of seizures, must give with food. A single dose of BRAVECTO Topical Solution for Dogs should be given by parting the dog's hair and applying the product directly to the skin between the shoulder blades. BRAVECTO Flea and Tick Warning A widely-shared Facebook post sought to warn pet owners that BRAVECTO chewable flea and tick remedy is supposedly harmful to dogs. Keep this and all drugs out of the reach of children. Personally I have sold over 5,000 doses and I have had two dogs vomit and have not seen any other side effects. All lab data collected from all dogs was normal. This FAQ compares all the currently available flea control products to assist you in determining which is right for your situation. Sarolaner: LD50 in rats, for skin exposure is >2020 mg/kg. These products are available at licensed veterinary hospitals. Bravecto Chews eliminates current flea infestations and prevents new ones from developing for 12 week…